DBDS
DBDS
CTDS
CTDS
TDDS
TDDS
TFDS
TFDS
CAPSEAL®
CAPSEAL®
BIOXC
BIOXC

ACNOTRIX®

UPCYCLED ACTIVE DELIVERY SYSTEM (CAPSEAL2X)

NANOVESICLES WITH 2% TANNIC ACID AND 8% COCOS NUCIFERA FRUIT EXTRACT

Made from 100% natural compounds, this skin-friendly ingredient boosts bioavailability and efficacy while ensuring excellent stability against light, heat, and homogenization during formulation.

  • ANTI-ACNE
  • ANTI-INFLAMMATION
  • ATOPIC DERMATITIS
  • WOUND HEALING
Mode of Action

Mode of Action

 

Regulating the activation receptor TLR-4

Downregulates TLR-4 mediated inflammatory signaling, suppressing pro-inflammatory cytokine release and reducing acne-associated skin inflammation.

 

Inhibiting the cytokine IL-1, IL-6, IL-8, TNF-α

Modulates upstream inflammatory pathways, suppressing IL-1, IL-6, IL-8, and TNF-α expression to attenuate acne-associated inflammatory responses and skin irritation.

 

Inhibiting the expression of NF-kB and NRF2

Modulates redox-inflammatory signaling by suppressing NF-κB and NRF2 expression, thereby attenuating oxidative stress and acne-associated inflammatory responses in skin.

Key Ingredient

Key Ingredient for skin

 

TANNIC ACID

Tannic acid provides antioxidant, anti-inflammatory, astringent, and antimicrobial effects, helping protect skin, reduce irritation, refine surface texture, and support barrier recovery.

 

AVOCADO OIL

Avocado oil delivers emollient, anti-inflammatory, antioxidant, and barrier-supporting effects, helping moisturize skin, reduce irritation, and support wound healing and tissue repair.

Nanovesicle Results

Nanovesicle results

 

152 nm.

AVERAGE NANOPARTICLE SIZE

 

-55 mV.

ZETA POTENTIAL

 

96%

ENTRAPMENT EFFICACY

Benefit of Nano­encapsulation

Benefit of Nanoencapsulation

 

A powerful botanical synergy is delivered through CAPSEAL2X technology, an advanced double-encapsulation system. Its inner modified liposome shields the actives from sunlight and promotes delivery into deeper skin layers, while the outer HydroLipidix biofilm, a natural polymer coating, enhances bioavailability, improves water dispersibility, and helps guard the actives against heat degradation.

INCI & Dosage

INCI, Dosage & Recommendation

 

INCI : TANIC ACID, COCOS NUCIFERA FRUIT EXTRACT, AVOCADO OIL and others (Please contact us to get more information)

 

RECOMMEND DOSAGE : 3 – 20%

 

CONCERN POINT :
– Incompatible with strong acids, bases, oxidizers and reducers.
– Recommended pH range between 2.0 and 7.5 to avoid conformational changes.

ACNOTRIX®

UPCYCLED ACTIVE DELIVERY SYSTEM (CAPSEAL2X)

ACNOTRIX is powered by CAPSEAL2X, a premium double-encapsulation technology that delivers Tannic acid and Avocado oil into deep skin layers. Its lipid-core, polymer-stabilized structure enhances stability, bioavailability, and bio-performance, helping soothe inflammation, defend against oxidative stress, and visibly improve skin clarity and tone.

BIO-efficacy & in-vivo results

480% Inhibition of P.acnes lipase activity greater than Azelaic acid
20X Enhance skin penetration greater than Tannic acid
85% Satisfaction with reduced old acne marks and dark spots
98% Satisfaction with reduction of inflammatory acne
94% Satisfaction with reduced post-acne dark and red marks on the face

SIMILAR PRODUCTS