NANOVESICLES WITH 0.5% HESPERIDIN AND CITRUS RETICULATA PEEL EXTRACT
Made from 100% natural compounds, this skin-friendly ingredient boosts bioavailability and efficacy while ensuring excellent stability against light, heat, and homogenization during formulation.
Suppresses IL-6 expression, downregulating JAK/STAT3-mediated inflammatory signaling and indirectly reducing melanogenesis-related pathways.
Inhibits tyrosinase activity, suppressing early-stage melanogenesis and reducing melanin production in melanocytes.
Provides antioxidant protection by neutralizing ROS, thereby minimizing oxidative damage and downstream inflammation-associated melanogenic responses.
Hesperidin provides antioxidant, anti-inflammatory, photoprotective, barrier-supporting, and depigmenting effects, helping reduce oxidative damage, calm cutaneous inflammation, improve pigmentation control, and support skin repair.
AVERAGE NANOPARTICLE SIZE
ZETA POTENTIAL
ENTRAPMENT EFFICACY
A powerful botanical synergy is delivered through CAPSEAL2X technology, an advanced double-encapsulation system. Its inner modified liposome shields the actives from sunlight and promotes delivery into deeper skin layers, while the outer HydroLipidix biofilm, a natural polymer coating, enhances bioavailability, improves water dispersibility, and helps guard the actives against heat degradation.
INCI : HEPERIDIN, CITRUS RETICULATA PEEL EXTRACT and others (Please contact us to get more information)
RECOMMEND DOSAGE : 3 – 20%
CONCERN :
– Incompatible with strong acids, bases, oxidizers and reducers.
– Recommended pH range between 2.0 and 7.5 to avoid conformational changes.
ORENIX is powered by CAPSEAL2X, a premium double-encapsulation technology that delivers HESPERIDIN into deep skin layers. Its lipid-core, polymer-stabilized structure enhances stability, bioavailability, and bio-performance, helping soothe inflammation, defend against oxidative stress, and visibly improve skin clarity and tone.
