DBDS
DBDS
CTDS
CTDS
TDDS
TDDS
TFDS
TFDS
CAPSEAL®
CAPSEAL®
BIOXC
BIOXC

ADEPEP®

TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS)

NANOVESICLES WITH 5% ADENOSINE COMPLEX + 5% NIACINAMIDE with 5,000 ppm COPPER TRIPEPTIDE-1

An innovation designed for the deepest dermal routine, featuring 100–300 nm lipid bilayer shell technology that is highly compatible with the skin’s stratum corneum. It is engineered for controlled and slow release into the dermal layer, while enhancing bioavailability and bio-efficacy, and offering high stability against light, heat, and high-shear processing.

  • AGE-DEFYING
  • SKIN-REJUVENATION
  • INFLAMMATION-MODULATING
  • BRIGHTENING
Mode of Action

Mode of Action

Adenosine electron donation

The NH₂ groups of adenosine act as electron-donating groups, supporting its biological activity.

 

Tyrosinase inhibitor activity

Helps inhibit tyrosinase activity, reducing melanin formation for a brighter-looking complexion.

 

Increase collagen production

Promotes collagen production, supporting skin firmness and elasticity.

 

Reduce inflammatory cytokines.

Helps reduce inflammatory cytokines, supporting calmer and healthier-looking skin.

 

Key Ingredient

Key Ingredient for skin

 

ADENOSINE COMPLEX

Adenosine supports skin repair processes by activating cellular signaling pathways, helping improve collagen synthesis, enhance skin firmness, and reduce the appearance of fine lines and wrinkles

 

ADENOSINE TRIPHOSPHATE

ATP acts as an energy source for cellular metabolism, supporting skin renewal processes, improving skin vitality, and enhancing overall skin condition.

 

NIACINAMIDE

Enhances ceramide synthesis to improve skin barrier function, reduces melanosome transfer to promote more even skin tone, and supports healthier-looking skin.

 

COPPER TRIPEPTIDE-1

A biomimetic peptide that supports fibroblast activity and extracellular matrix (ECM) synthesis, promoting collagen production and improving skin elasticity and resilience.

Nanovesicle Results

Nanovesicle results

 

120 nm.

AVERAGE NANOPARTICLE SIZE

 

-46 mV.

ZETA POTENTIAL

 

98%

ENTRAPMENT EFFICACY

Benefit of Nano­encapsulation

Benefit of Nanoencapsulation

Optimized Penetration Dimension with 100 – 300 nm , each niosome is small enough to navigate the intercellular lipid pathway of the stratum corneum while remaining large enough to avoid systemic absorption, maintaining a topical-localized action. It’s enhanced deposition in the viable epidermis and upper dermis and superior bioavailability of both hydrophilic and lipophilic actives through dual-phase distribution.

INCI & Dosage

INCI, Dosage & Recommendation

INCI : NIACINAMIDE, ADENOSINE TRIPHOSPHATE, ADENOSINE, COPPER TRIPEPTIDE-1, and others (Please contact us to get more information)

 

RECOMMEND DOSAGE : 3 – 20%

 

CONCERN :
– Incompatible with strong acids, bases, oxidizers and reducers.
– Recommended pH range between 5.0 and 8.0 to avoid conformational changes.

ADEPEP®

TRANSDERMAL DRUG DELIVERY SYSTEM (TDDS)

TDDS offered the controlled release diffusion with deepest penetration to deliver encapsulated active ingredients through stratum corneum barrier functioned to target cells as Melanocyte, Keratinocyte, Basal layer, Fibroblast and Mast cells.

BIO-efficacy & in-vivo results

6.8X Greater than free adenosine complex.
7.8X Greater than free Niacinamide
15X Enhance skin penetration greater than free adenosine
89% Satisfaction of skin smoothness
69% Satisfaction of skin brightness

SIMILAR PRODUCTS