NANOVESICLES WITH 6% TRANEXAMIC ACID with 4% NIACINAMIDE
An innovation designed for the deepest dermal routine, featuring 100–300 nm lipid bilayer shell technology that is highly compatible with the skin’s stratum corneum. It is engineered for controlled and slow release into the dermal layer, while enhancing bioavailability and bio-efficacy, and offering high stability against light, heat, and high-shear processing.
Modulates cellular signaling between keratinocytes and melanocytes to reduce melanin production.
Inhibits tyrosinase activity in melanocytes, helping reduce excessive pigmentation.
Downregulates the formation of L-DOPA and dopaquinone, key intermediates in melanin synthesis.
Inhibits plasmin activity in keratinocytes, reducing melanogenic signaling and subsequent melanin production.
Helps regulate pigmentation pathways by inhibiting plasmin-mediated signaling in melanocytes, reducing UV-induced melanin production and improving the appearance of dark spots and uneven skin tone.
Enhances ceramide synthesis to strengthen the skin barrier, reduces melanosome transfer to improve skin tone uniformity, and supports healthier-looking skin.
AVERAGE NANOPARTICLE SIZE
ZETA POTENTIAL
ENTRAPMENT EFFICACY
Optimized Penetration Dimension with 100 – 300 nm , each niosome is small enough to navigate the intercellular lipid pathway of the stratum corneum while remaining large enough to avoid systemic absorption, maintaining a topical-localized action. It’s enhanced deposition in the viable epidermis and upper dermis and superior bioavailability of both hydrophilic and lipophilic actives through dual-phase distribution.
INCI : NIACINAMIDE, ADENOSINE TRIPHOSPHATE, ADENOSINE, COPPER TRIPEPTIDE-1, and others (Please contact us to get more information)
RECOMMEND DOSAGE : 3 – 20%
CONCERN :
– Incompatible with strong acids, bases, oxidizers and reducers.
– Recommended pH range between 5.0 and 8.0 to avoid conformational changes.
TDDS offered the controlled release diffusion with deepest penetration to deliver encapsulated active ingredients through stratum corneum barrier functioned to target cells as Melanocyte, Keratinocyte, Basal layer, Fibroblast and Mast cells.
